NK/T 细胞增殖性疾病 XX 医院血液科XX202X.X.XT 和 NK 细胞肿瘤的分类：WHO 2008 WHO 2008: the mature T-cell and NK-cell neoplasms T-cell prolymphocytic leukemia T-cell large granular lymphocytic leukemia Chronic lymphoproliferative disorder of NK-cells* Aggressive NK cell leukemia Systemic EBV+ T-cell lymphoproliferative disease of childhood (associated with CAEBV) Hydroa vacciniforme-like lymphoma Adult T-cell leukemia/lymphoma Extranodal NK/T cell lymphoma, nasal type Enteropathy-associated T-cell lymphoma Hepatosplenic T-cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Mycosis fungoides Sézary syndrome Primary cutaneous CD30+ T-cell lymphoproliferative disorder Lymphomatoid papulosis Primary cutaneous anaplastic large-cell lymphoma Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma* Primary cutaneous gamma-delta T-cell lymphoma Primary cutaneous small/medium CD4+ T-cell lymphoma* Peripheral T-cell lymphoma, not otherwise specified Angioimmunoblastic T-cell lymphoma Anaplastic large cell lymphoma (ALCL), ALK+ Anaplastic large cell lymphoma (ALCL), ALK?* 2001 WHO 2008 WHO Comments Angioimmunoblastic Lymphoma Angioimmunoblastic Lymphoma Definition of origin cell Anaplastic Large Cell Lymphoma 2 variants based on ALK (+/-) expression Prognostic importance Unspecified Peripheral T-cell Lymphoma Peripheral T-cell Lymphomas not Otherwise Specified 3 variants: lymphoepitelioid lymphoma, T zone lymphoma (2001 WHO) and follicular lymphoma (2008 WHO) T/NK-cell lymphoma, nasal type T/NK-cell lymphoma, nasal type No changes Entheropathy-associated T-cell lymphoma Entheropathy-associated T-cell lymphomas Two variants: classical and monomorphic types with genetic changes common to both Hepatosplenic T-cell lymphoma Hepatosplenic T-cell lymph...
