POSITION PAPERUK clinical guideline for the prevention and treatment of osteoporosisJ. Compston 1 & A. Cooper 2 & C. Cooper3 & N. Gittoes 4 & C. Gregson 5 & N. Harvey3 &S. Hope 6 & J. A. Kanis 7 & E. V. McCloskey 8 & K. E. S. Poole 1 & D. M. Reid 9 & P. Selby 10 &F. Thompson 11 & A. Thurston 11 & N. Vine 1 & The National Osteoporosis Guideline Group (NOGG)AbstractIntroduction In 2008, the UK National Osteoporosis Guideline Group (NOGG) produced a guideline on the prevention and treatment of osteoporosis, with an update in 2013. This paper presents a major update of the guideline, the scope of which is to review the assessment and management of osteoporosis andthe prevention of fragility fractures in postmenopausal women and men age 50 years or over.Methods Where available, systematic reviews, meta-analyses and randomised controlled trials were used to provide the evi- dence base. Conclusions and recommendations were systemati- cally graded according to the strength of the available evidence.Affiliations of the NOGG writing group are provided in Appendix 1 Results Review of the evidence and recommendations areprovided for the diagnosis of osteoporosis, fracture-risk as- sessment, lifestyle measures and pharmacological interven- tions, duration and monitoring of bisphosphonate therapy, glucocorticoid-induced osteoporosis, osteoporosis in men,postfracture care and intervention thresholds.Conclusion The guideline, which has received accreditation from the National Institute of Health and Care Excellence (NICE), provides a comprehensive overview of the assess- ment and management of osteoporosis for all healthcare pro- fessionals who are involved in its management.Keywords Osteoporosis . Fracture . NOGG . GuidelineIntroductionThis updated guideline provides guidance on the prevention and treatment of osteoporosis in the UK. It updates guidelines previously developed by the Royal College of Physicians [1, 2] and the National Osteoporosis Guideline Group [3, 4]. The scope of the guideline is to review the assessment and diag- nosis of osteoporosis, the therapeutic interventions available and the manner in which these can be used to develop man- agement strategies for the prevention of fragility fracture in postmenopausal women and in men age 50 years or over. The guideline was prepared by a writing group (Appendix 1) and finalised after consultation with stakeholders (Appendix 2).The guideline is intended for all healthcare professionals involved in the management of osteoporosis. The conclusions and recommendations in the document are systematically graded, according to the quality of information available, to indicate the level of evidence on which recommendations are based. The grading methodology is summarised in Appendix 3. Where available, systematic reviews, meta-analyses and randomised controlled trials have been used to provide the evidence base...
