. 诊疗指南 .多发性骨髓瘤骨病外科治疗循证医学指南【摘要】大部分多发性骨髓瘤患者在病程中会出现骨髓瘤骨病，严重影响患者的生活质量和生存率。规范的化疗、靶向治疗和双膦酸盐是治疗多发性骨髓瘤骨病的基础和最重要的部分。外科手术在多发性骨髓瘤骨病急性并发症（病理性骨折、脊柱不稳和脊髓压迫症等）的治疗中发挥着重要作用。中国医师协会骨科医师分会骨肿瘤专业委员会依据循证医学方法制定了《多发性骨髓瘤骨病外科治疗循证医学指南》，分别就外科治疗时机、手术指征、不同部位的手术方式及综合治疗等临床问题进行总结，依据文献证据等级给出相应的推荐等级。专业委员会希望本指南能够为骨肿瘤医师的临床诊疗提供最佳的、有效的意见参考，从而使患者达到最佳的治疗效果。而本指南仅为学术性指导意见，具体实施时必须依据患者的个体医疗情况而定。Guideline for evidence based⁃ surgical treatment of multiple myeloma bone diseaseMusculoskeletal Tumor Society, Chinese Association of Orthopaedic SurgeonsGUO Wei1*, NIU Xiaohui2, XIAO Jianru3, LI Jianmin4, WANG Zhen5, SHEN Jingnan6, SHAO Zengwu7,ZHANG Weibin8, YE Zhaoming9, WU Sujia10, TU Chongqi11, LU Jin12, CHEN Wenming13, DU Xinru14, YANG Yi1(1.Musculoskeletal Tumor Center, Peking University People's Hospital, Beijing 100044; 2.Department of Orthopaedic On- cology, JIshuitan Hospital, Beijing 100035; 3.Department of Orthopaedics, Shanghai Changzheng Hospital, Shanghai 200003; 4.Department of Orthopaedics, Qilu Hospital of Shandong University, Ji'nan 250012; 5.Department of Orthopae- dics, Xijing Hospital, Air Force Medical University, Xi′an 710032; 6.Department of Orthopaedics, The First Affiliated Hos- pital of Sun Yat-sen University, Guangzhou 510080; 7.Department of Orthopaedics, Union Hospital, Tongji Medical Col- lege, Huazhong University of Science and Technology, Wuhan 430022; 8.Department of Orthopaedics, Shanghai Ruijin Hospital, Shanghai 200025; 9.Department of Orthopaedics, The Second Affiliated Hospital, Zhejiang Univer...
